TY - GEN AU - Bu,De-xiu AU - Tarrio,Margarite AU - Maganto-Garcia,Elena AU - Stavrakis,George AU - Tajima,Goro AU - Lederer,James AU - Jarolim,Petr AU - Freeman,Gordon J AU - Sharpe,Arlene H AU - Lichtman,Andrew H TI - Impairment of the programmed cell death-1 pathway increases atherosclerotic lesion development and inflammation SN - 1524-4636 PY - 2011///0624 KW - Animals KW - Antibodies, Blocking KW - pharmacology KW - Antigens, Surface KW - genetics KW - Apoptosis KW - Apoptosis Regulatory Proteins KW - antagonists & inhibitors KW - Atherosclerosis KW - B7-1 Antigen KW - B7-H1 Antigen KW - Bone Marrow Transplantation KW - CD3 Complex KW - metabolism KW - CD4-Positive T-Lymphocytes KW - immunology KW - CD8-Positive T-Lymphocytes KW - Cell Proliferation KW - Cells, Cultured KW - Disease Models, Animal KW - Genes, T-Cell Receptor KW - Genotype KW - Hypercholesterolemia KW - Inflammation KW - Lipoproteins, LDL KW - Lymph Nodes KW - Lymphocyte Activation KW - drug effects KW - Macrophages KW - Male KW - Membrane Glycoproteins KW - deficiency KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Peptides KW - Phenotype KW - Programmed Cell Death 1 Ligand 2 Protein KW - Programmed Cell Death 1 Receptor KW - Receptors, LDL KW - Signal Transduction KW - T-Lymphocyte Subsets KW - T-Lymphocytes, Cytotoxic KW - Time Factors KW - Tumor Necrosis Factor-alpha KW - blood N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1161/ATVBAHA.111.224709 ER -