AKT kinase activity is required for lithium to modulate mood-related behaviors in mice. [electronic resource]
- Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Jun 2011
- 1397-411 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1740-634X
10.1038/npp.2011.24 doi
Amphetamine--adverse effects Analysis of Variance Animals Antimanic Agents--pharmacology Cell Line, Transformed Corpus Striatum--drug effects Disease Models, Animal Drug Administration Routes Drug Administration Schedule Drug Interactions Enzyme Inhibitors--pharmacology Gene Expression Regulation, Enzymologic--drug effects Glycogen Synthase Kinase 3--genetics Glycogen Synthase Kinase 3 beta Hippocampus--cytology Humans Lithium Chloride--pharmacology Male Mice Mice, Inbred C57BL Mice, Inbred DBA Mood Disorders--chemically induced Proto-Oncogene Proteins c-akt--genetics Signal Transduction--drug effects Transfection--methods