TY  - GEN
AU  - Evdokimov,Nikolai M
AU  - Van Slambrouck,Severine
AU  - Heffeter,Petra
AU  - Tu,Lee
AU  - Le Calvé,Benjamin
AU  - Lamoral-Theys,Delphine
AU  - Hooten,Carla J
AU  - Uglinskii,Pavel Y
AU  - Rogelj,Snezna
AU  - Kiss,Robert
AU  - Steelant,Wim F A
AU  - Berger,Walter
AU  - Yang,Jeremy J
AU  - Bologa,Cristian G
AU  - Kornienko,Alexander
AU  - Magedov,Igor V
TI  - Structural simplification of bioactive natural products with multicomponent synthesis. 3. Fused uracil-containing heterocycles as novel topoisomerase-targeting agents
SN  - 1520-4804
PY  - 2011///0606
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Biological Products
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - DNA Topoisomerases, Type I
KW  - metabolism
KW  - DNA Topoisomerases, Type II
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Topoisomerase II Inhibitors
KW  - Uracil
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm1009428
ER  -