Procopiou, Panayiotis A <br/><br/>
The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis.  [electronic resource] 

 -  Journal of medicinal chemistry  Apr 2011 
 - 2183-95 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm1013874  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Intranasal<br/>Administration, Oral<br/>Drug Discovery--methods<br/>Histamine H1 Antagonists--administration & dosage<br/>Histamine H3 Antagonists--administration & dosage<br/>Humans<br/>Models, Molecular<br/>Phthalazines--administration & dosage<br/>Protein Conformation<br/>Receptors, Histamine H1--chemistry<br/>Receptors, Histamine H3--metabolism<br/>Rhinitis--drug therapy