Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. [electronic resource]
- PLoS genetics Feb 2011
- e1001308 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1553-7404
10.1371/journal.pgen.1001308 doi
Adaptor Proteins, Signal Transducing--genetics Aged Alzheimer Disease--genetics Apolipoproteins E--genetics CELF Proteins Case-Control Studies Clusterin--genetics Family Gene Frequency--genetics Genetic Predisposition to Disease Genome, Human--genetics Genome-Wide Association Study Heterozygote Humans Middle Aged Nerve Tissue Proteins--genetics Nuclear Proteins--genetics Polymorphism, Single Nucleotide--genetics Population Dynamics Principal Component Analysis Protein Binding RNA-Binding Proteins--genetics Reproducibility of Results Tumor Suppressor Proteins--genetics White People--genetics