TY  - GEN
AU  - Abad,Marta C
AU  - Gibbs,Alan C
AU  - Zhang,Xuqing
TI  - Electron density guided fragment-based drug design--a lead generation example
SN  - 1557-7988
PY  - 2011///0616
KW  - Adenosine Triphosphate
KW  - metabolism
KW  - Adenylyl Imidodiphosphate
KW  - Catalytic Domain
KW  - drug effects
KW  - Crystallography, X-Ray
KW  - Drug Design
KW  - Drug Discovery
KW  - Drug Evaluation, Preclinical
KW  - methods
KW  - Electrons
KW  - Enzyme Inhibitors
KW  - chemistry
KW  - Fructokinases
KW  - antagonists & inhibitors
KW  - Fructose
KW  - Hydrogen Bonding
KW  - Models, Molecular
KW  - Protein Binding
KW  - Small Molecule Libraries
KW  - Sulfates
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1016/B978-0-12-381274-2.00019-4
ER  -