TY - GEN AU - Trzeciakiewicz,Anna AU - Fortin,Sébastien AU - Moreau,Emmanuel AU - C-Gaudreault,René AU - Lacroix,Jacques AU - Chambon,Christophe AU - Communal,Yves AU - Chezal,Jean-Michel AU - Miot-Noirault,Elisabeth AU - Bouchon,Bernadette AU - Degoul,Françoise TI - Intramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40 SN - 1873-2968 PY - 2011///0606 KW - Alkylating Agents KW - pharmacology KW - Amines KW - chemistry KW - Animals KW - Aspartic Acid KW - metabolism KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Chromatography, High Pressure Liquid KW - Cyclization KW - Electrophoresis, Gel, Two-Dimensional KW - Fluorescent Antibody Technique KW - Glutamic Acid KW - Melanoma, Experimental KW - pathology KW - Mice KW - Prohibitins KW - Repressor Proteins KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization KW - Tubulin KW - Urea N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bcp.2011.02.014 ER -