Trzeciakiewicz, Anna <br/><br/>
Intramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40.  [electronic resource] 

 -  Biochemical pharmacology  May 2011 
 - 1116-23 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1873-2968 
<br/><br/><label>Standard No.: </label>10.1016/j.bcp.2011.02.014  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alkylating Agents--pharmacology<br/>Amines--chemistry<br/>Animals<br/>Aspartic Acid--metabolism<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Chromatography, High Pressure Liquid<br/>Cyclization<br/>Electrophoresis, Gel, Two-Dimensional<br/>Fluorescent Antibody Technique<br/>Glutamic Acid--metabolism<br/>Melanoma, Experimental--pathology<br/>Mice<br/>Prohibitins<br/>Repressor Proteins--chemistry<br/>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization<br/>Tubulin--chemistry<br/>Urea--chemistry