Li, Li

Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts. [electronic resource] - Cardiovascular research Jul 2011 - 80-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1755-3245

10.1093/cvr/cvr067 doi


Analysis of Variance
Angiotensin II--administration & dosage
Angiotensin II Type 1 Receptor Blockers--pharmacology
Animals
Cell Adhesion Molecules--genetics
Cells, Cultured
Cyclic AMP Response Element-Binding Protein--metabolism
DNA-Binding Proteins--metabolism
Fibroblasts--drug effects
Fibrosis
Guanine Nucleotide Exchange Factors--metabolism
Infusions, Subcutaneous
Losartan--pharmacology
Male
Mitogen-Activated Protein Kinase 1--antagonists & inhibitors
Mitogen-Activated Protein Kinase 3--antagonists & inhibitors
Myocardium--enzymology
Phosphorylation
Protein Kinase Inhibitors--pharmacology
RNA Interference
RNA, Messenger--metabolism
Rats
Rats, Sprague-Dawley
Signal Transduction
Smad2 Protein--metabolism
Smad3 Protein--metabolism
Time Factors
Transfection
Transforming Growth Factor beta1--metabolism
Up-Regulation
p38 Mitogen-Activated Protein Kinases--antagonists & inhibitors
ras Proteins--genetics