TY  - GEN
AU  - Honda,Tadashi
AU  - Yoshizawa,Hidenori
AU  - Sundararajan,Chitra
AU  - David,Emilie
AU  - Lajoie,Marc J
AU  - Favaloro,Frank G
AU  - Janosik,Tomasz
AU  - Su,Xiaobo
AU  - Honda,Yukiko
AU  - Roebuck,Bill D
AU  - Gribble,Gordon W
TI  - Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents
SN  - 1520-4804
PY  - 2011///0617
KW  - Aflatoxin B1
KW  - Animals
KW  - Anti-Inflammatory Agents, Non-Steroidal
KW  - chemical synthesis
KW  - Antineoplastic Agents
KW  - Cells, Cultured
KW  - Cytoprotection
KW  - Enzyme Induction
KW  - Heme Oxygenase-1
KW  - biosynthesis
KW  - Interferon-gamma
KW  - pharmacology
KW  - Liver
KW  - drug effects
KW  - Liver Neoplasms, Experimental
KW  - chemically induced
KW  - Macrophages
KW  - Male
KW  - Mice
KW  - NAD(P)H Dehydrogenase (Quinone)
KW  - Nitric Oxide Synthase Type II
KW  - antagonists & inhibitors
KW  - Nitriles
KW  - Pentacyclic Triterpenes
KW  - chemistry
KW  - Phenanthrenes
KW  - Precancerous Conditions
KW  - Rats
KW  - Stereoisomerism
KW  - Stomach
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm101445p
ER  -