Honda, Tadashi <br/><br/>
Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents.  [electronic resource] 

 -  Journal of medicinal chemistry  Mar 2011 
 - 1762-78 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm101445p  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aflatoxin B1<br/>Animals<br/>Anti-Inflammatory Agents, Non-Steroidal--chemical synthesis<br/>Antineoplastic Agents--chemical synthesis<br/>Cells, Cultured<br/>Cytoprotection<br/>Enzyme Induction<br/>Heme Oxygenase-1--biosynthesis<br/>Interferon-gamma--pharmacology<br/>Liver--drug effects<br/>Liver Neoplasms, Experimental--chemically induced<br/>Macrophages--drug effects<br/>Male<br/>Mice<br/>NAD(P)H Dehydrogenase (Quinone)--biosynthesis<br/>Nitric Oxide Synthase Type II--antagonists & inhibitors<br/>Nitriles--chemical synthesis<br/>Pentacyclic Triterpenes--chemistry<br/>Phenanthrenes--chemical synthesis<br/>Precancerous Conditions--chemically induced<br/>Rats<br/>Stereoisomerism<br/>Stomach--drug effects<br/>Structure-Activity Relationship