TY  - GEN
AU  - Opel,Daniela
AU  - Naumann,Ivonne
AU  - Schneider,Maxi
AU  - Bertele,Daniela
AU  - Debatin,Klaus-Michael
AU  - Fulda,Simone
TI  - Targeting aberrant PI3K/Akt activation by PI103 restores sensitivity to TRAIL-induced apoptosis in neuroblastoma
SN  - 1557-3265
PY  - 2011///1007
KW  - Animals
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - therapeutic use
KW  - Apoptosis
KW  - drug effects
KW  - Brain Neoplasms
KW  - drug therapy
KW  - Chick Embryo
KW  - Drug Resistance, Neoplasm
KW  - Drug Synergism
KW  - Enzyme Activation
KW  - genetics
KW  - Furans
KW  - administration & dosage
KW  - Humans
KW  - Mice
KW  - Molecular Targeted Therapy
KW  - Mutation
KW  - physiology
KW  - Neuroblastoma
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Protein Kinase Inhibitors
KW  - Proto-Oncogene Proteins c-akt
KW  - antagonists & inhibitors
KW  - Pyridines
KW  - Pyrimidines
KW  - TNF-Related Apoptosis-Inducing Ligand
KW  - Tumor Cells, Cultured
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/1078-0432.CCR-10-2530
ER  -