TY  - GEN
AU  - Yu,Jing
AU  - Karcher,Helene
AU  - Feire,Adam L
AU  - Lowe,Philip J
TI  - From target selection to the minimum acceptable biological effect level for human study: use of mechanism-based PK/PD modeling to design safe and efficacious biologics
SN  - 1550-7416
PY  - 2011///0826
KW  - Animals
KW  - Antibodies, Monoclonal
KW  - administration & dosage
KW  - Cytomegalovirus
KW  - immunology
KW  - Dose-Response Relationship, Drug
KW  - Drug Delivery Systems
KW  - Drug Design
KW  - Feasibility Studies
KW  - Glycoproteins
KW  - Humans
KW  - Immunologic Factors
KW  - Macaca fascicularis
KW  - Models, Biological
KW  - Species Specificity
KW  - Translational Research, Biomedical
KW  - methods
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1208/s12248-011-9256-y
ER  -