Yu, Jing <br/><br/>
From target selection to the minimum acceptable biological effect level for human study: use of mechanism-based PK/PD modeling to design safe and efficacious biologics.  [electronic resource] 

 -  The AAPS journal  Jun 2011 
 - 169-78 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1550-7416 
<br/><br/><label>Standard No.: </label>10.1208/s12248-011-9256-y  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies, Monoclonal--administration & dosage<br/>Cytomegalovirus--immunology<br/>Dose-Response Relationship, Drug<br/>Drug Delivery Systems<br/>Drug Design<br/>Feasibility Studies<br/>Glycoproteins--immunology<br/>Humans<br/>Immunologic Factors--administration & dosage<br/>Macaca fascicularis<br/>Models, Biological<br/>Species Specificity<br/>Translational Research, Biomedical--methods