TY - GEN AU - Huang,RenFa AU - Zhou,QiaoLing AU - Veeraragoo,Pouranan AU - Yu,HongLei AU - Xiao,Zhou TI - Notch2/Hes-1 pathway plays an important role in renal ischemia and reperfusion injury-associated inflammation and apoptosis and the γ-secretase inhibitor DAPT has a nephroprotective effect SN - 1525-6049 PY - 2011///0616 KW - Acute Kidney Injury KW - metabolism KW - Amyloid Precursor Protein Secretases KW - antagonists & inhibitors KW - Animals KW - Apoptosis KW - drug effects KW - Basic Helix-Loop-Helix Transcription Factors KW - Cytokines KW - Dipeptides KW - pharmacology KW - Epithelial Cells KW - Homeodomain Proteins KW - In Situ Nick-End Labeling KW - Inflammation KW - drug therapy KW - Kidney KW - Kidney Function Tests KW - Male KW - NF-kappa B KW - Rats KW - Rats, Sprague-Dawley KW - Receptor, Notch2 KW - Reperfusion Injury KW - Signal Transduction KW - Transcription Factor HES-1 KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article UR - https://doi.org/10.3109/0886022X.2011.553979 ER -