Huang, RenFa <br/><br/>
Notch2/Hes-1 pathway plays an important role in renal ischemia and reperfusion injury-associated inflammation and apoptosis and the γ-secretase inhibitor DAPT has a nephroprotective effect.  [electronic resource] 

 -  Renal failure  2011 
 - 207-16 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1525-6049 
<br/><br/><label>Standard No.: </label>10.3109/0886022X.2011.553979  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acute Kidney Injury--metabolism<br/>Amyloid Precursor Protein Secretases--antagonists & inhibitors<br/>Animals<br/>Apoptosis--drug effects<br/>Basic Helix-Loop-Helix Transcription Factors--metabolism<br/>Cytokines--metabolism<br/>Dipeptides--pharmacology<br/>Epithelial Cells--drug effects<br/>Homeodomain Proteins--metabolism<br/>In Situ Nick-End Labeling<br/>Inflammation--drug therapy<br/>Kidney--drug effects<br/>Kidney Function Tests<br/>Male<br/>NF-kappa B--metabolism<br/>Rats<br/>Rats, Sprague-Dawley<br/>Receptor, Notch2--metabolism<br/>Reperfusion Injury--metabolism<br/>Signal Transduction<br/>Transcription Factor HES-1<br/>bcl-2-Associated X Protein--metabolism