TY - GEN AU - Khan,O A AU - Gore,M AU - Lorigan,P AU - Stone,J AU - Greystoke,A AU - Burke,W AU - Carmichael,J AU - Watson,A J AU - McGown,G AU - Thorncroft,M AU - Margison,G P AU - Califano,R AU - Larkin,J AU - Wellman,S AU - Middleton,M R TI - A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours SN - 1532-1827 PY - 2011///0419 KW - Adult KW - Aged KW - Antineoplastic Combined Chemotherapy Protocols KW - adverse effects KW - Dacarbazine KW - administration & dosage KW - Drug Administration Schedule KW - Female KW - Humans KW - Male KW - Maximum Tolerated Dose KW - Melanoma KW - drug therapy KW - Middle Aged KW - Neoplasms KW - Neutropenia KW - chemically induced KW - Phthalazines KW - Piperazines KW - Poly(ADP-ribose) Polymerase Inhibitors KW - Thrombocytopenia N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/bjc.2011.8 ER -