TY - GEN AU - Deb,Tushar B AU - Zuo,Annie H AU - Wang,Youhong AU - Barndt,Robert J AU - Cheema,Amrita K AU - Sengupta,Surojeet AU - Coticchia,Christine M AU - Johnson,Michael D TI - Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex SN - 1522-1563 PY - 2011///0726 KW - Benzoquinones KW - pharmacology KW - Calcium-Calmodulin-Dependent Protein Kinase Type 1 KW - genetics KW - Cell Proliferation KW - drug effects KW - Cyclin-Dependent Kinase Inhibitor p21 KW - metabolism KW - Enzyme Inhibitors KW - ErbB Receptors KW - HEK293 Cells KW - HSP90 Heat-Shock Proteins KW - antagonists & inhibitors KW - Humans KW - Lactams, Macrocyclic KW - Mitogen-Activated Protein Kinases KW - Mutation KW - Phosphorylation KW - Proteasome Endopeptidase Complex KW - Serine KW - Threonine N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1152/ajpcell.00167.2010 ER -