TY - GEN AU - Horáková,D AU - Kýr,M AU - Havrdová,E AU - Doležal,O AU - Lelková,P AU - Pospíšilová,L AU - Bergsland,N AU - Dwyer,M G AU - Cox,J L AU - Hussein,S AU - Seidl,Z AU - Vaněčková,M AU - Krásenský,J AU - Zivadinov,R TI - Apolipoprotein E ε4-positive multiple sclerosis patients develop more gray-matter and whole-brain atrophy: a 15-year disease history model based on a 4-year longitudinal study SN - 0015-5500 PY - 2011///0627 KW - Adjuvants, Immunologic KW - therapeutic use KW - Adult KW - Anti-Inflammatory Agents KW - Apolipoprotein E4 KW - genetics KW - Atrophy KW - pathology KW - Azathioprine KW - Brain KW - Disease Progression KW - Drug Therapy, Combination KW - Female KW - Follow-Up Studies KW - Genotype KW - Humans KW - Image Processing, Computer-Assisted KW - Immunosuppressive Agents KW - Interferon beta-1a KW - Interferon-beta KW - Longitudinal Studies KW - Magnetic Resonance Imaging KW - Male KW - Multiple Sclerosis, Relapsing-Remitting KW - drug therapy KW - Nerve Fibers, Myelinated KW - Prednisone N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -