TY  - GEN
AU  - Williams,Richard
AU  - Manka,Jason T
AU  - Rodriguez,Alice L
AU  - Vinson,Paige N
AU  - Niswender,Colleen M
AU  - Weaver,C David
AU  - Jones,Carrie K
AU  - Conn,P Jeffrey
AU  - Lindsley,Craig W
AU  - Stauffer,Shaun R
TI  - Synthesis and SAR of centrally active mGlu5 positive allosteric modulators based on an aryl acetylenic bicyclic lactam scaffold
SN  - 1464-3405
PY  - 2011///0614
KW  - Allosteric Regulation
KW  - Animals
KW  - Antipsychotic Agents
KW  - chemical synthesis
KW  - Bridged Bicyclo Compounds
KW  - Inhibitory Concentration 50
KW  - Lactams
KW  - Molecular Structure
KW  - Rats
KW  - Receptors, Metabotropic Glutamate
KW  - metabolism
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2011.01.044
ER  -