Williams, Richard <br/><br/>
Synthesis and SAR of centrally active mGlu5 positive allosteric modulators based on an aryl acetylenic bicyclic lactam scaffold.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Mar 2011 
 - 1350-3 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2011.01.044  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Regulation<br/>Animals<br/>Antipsychotic Agents--chemical synthesis<br/>Bridged Bicyclo Compounds--chemical synthesis<br/>Inhibitory Concentration 50<br/>Lactams--chemical synthesis<br/>Molecular Structure<br/>Rats<br/>Receptors, Metabotropic Glutamate--metabolism<br/>Structure-Activity Relationship