TY  - GEN
AU  - Kawata,Hiromitsu
AU  - Arai,Shinichi
AU  - Nakagawa,Toshito
AU  - Ishikura,Nobuyuki
AU  - Nishimoto,Ayako
AU  - Yoshino,Hitoshi
AU  - Shiraishi,Takuya
AU  - Tachibana,Kazutaka
AU  - Nakamura,Ryo
AU  - Sato,Haruhiko
TI  - Biological properties of androgen receptor pure antagonist for treatment of castration-resistant prostate cancer: optimization from lead compound to CH5137291
SN  - 1097-0045
PY  - 2011///0926
KW  - Androgen Antagonists
KW  - pharmacokinetics
KW  - Androgen Receptor Antagonists
KW  - administration & dosage
KW  - Anilides
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Carbamates
KW  - Cell Nucleus
KW  - metabolism
KW  - Cell Proliferation
KW  - drug effects
KW  - Cells, Cultured
KW  - Dose-Response Relationship, Drug
KW  - Humans
KW  - Lead
KW  - Male
KW  - Mice
KW  - Mice, Nude
KW  - Mice, SCID
KW  - Neoplasm Transplantation
KW  - Nitriles
KW  - Orchiectomy
KW  - Prostatic Neoplasms
KW  - Receptors, Androgen
KW  - Sulfonamides
KW  - Thiohydantoins
KW  - Tosyl Compounds
KW  - Transcription, Genetic
KW  - Translocation, Genetic
KW  - Transplantation, Heterologous
N1  - Publication Type: Comparative Study; Journal Article
UR  - https://doi.org/10.1002/pros.21351
ER  -