Kawata, Hiromitsu <br/><br/>
Biological properties of androgen receptor pure antagonist for treatment of castration-resistant prostate cancer: optimization from lead compound to CH5137291.  [electronic resource] 

 -  The Prostate  Sep 2011 
 - 1344-56 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>1097-0045 
<br/><br/><label>Standard No.: </label>10.1002/pros.21351  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Androgen Antagonists--pharmacokinetics<br/>Androgen Receptor Antagonists--administration & dosage<br/>Anilides--pharmacokinetics<br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Carbamates--pharmacology<br/>Cell Nucleus--metabolism<br/>Cell Proliferation--drug effects<br/>Cells, Cultured<br/>Dose-Response Relationship, Drug<br/>Humans<br/>Lead<br/>Male<br/>Mice<br/>Mice, Nude<br/>Mice, SCID<br/>Neoplasm Transplantation<br/>Nitriles--metabolism<br/>Orchiectomy<br/>Prostatic Neoplasms--metabolism<br/>Receptors, Androgen--drug effects<br/>Sulfonamides--administration & dosage<br/>Thiohydantoins--administration & dosage<br/>Tosyl Compounds--pharmacokinetics<br/>Transcription, Genetic--drug effects<br/>Translocation, Genetic<br/>Transplantation, Heterologous