TY - GEN AU - Harismendy,Olivier AU - Notani,Dimple AU - Song,Xiaoyuan AU - Rahim,Nazli G AU - Tanasa,Bogdan AU - Heintzman,Nathaniel AU - Ren,Bing AU - Fu,Xiang-Dong AU - Topol,Eric J AU - Rosenfeld,Michael G AU - Frazer,Kelly A TI - 9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response SN - 1476-4687 PY - 2011///0228 KW - Alleles KW - Cell Line KW - Chromatin KW - drug effects KW - Chromosomes, Human, Pair 9 KW - genetics KW - Conserved Sequence KW - Coronary Artery Disease KW - Cyclin-Dependent Kinase Inhibitor p15 KW - Diabetes Mellitus, Type 2 KW - Endothelial Cells KW - Enhancer Elements, Genetic KW - Gene Expression Regulation KW - Gene Knockdown Techniques KW - Genetic Predisposition to Disease KW - Genetic Variation KW - Genome-Wide Association Study KW - Haplotypes KW - HeLa Cells KW - Humans KW - Interferon-alpha KW - Interferon-gamma KW - pharmacology KW - Linkage Disequilibrium KW - Male KW - Polymorphism, Single Nucleotide KW - Protein Binding KW - Purine-Nucleoside Phosphorylase KW - STAT1 Transcription Factor KW - biosynthesis KW - Signal Transduction KW - White People N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/nature09753 ER -