TY  - GEN
AU  - Yazawa,Masayuki
AU  - Hsueh,Brian
AU  - Jia,Xiaolin
AU  - Pasca,Anca M
AU  - Bernstein,Jonathan A
AU  - Hallmayer,Joachim
AU  - Dolmetsch,Ricardo E
TI  - Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
SN  - 1476-4687
PY  - 2011///0325
KW  - Action Potentials
KW  - drug effects
KW  - Autistic Disorder
KW  - Calcium Channels, L-Type
KW  - genetics
KW  - Calcium Signaling
KW  - Cell Transdifferentiation
KW  - Cellular Reprogramming
KW  - Drug Evaluation, Preclinical
KW  - methods
KW  - Fibroblasts
KW  - cytology
KW  - HEK293 Cells
KW  - Humans
KW  - Induced Pluripotent Stem Cells
KW  - pathology
KW  - Long QT Syndrome
KW  - drug therapy
KW  - Mutation, Missense
KW  - Myocytes, Cardiac
KW  - Patch-Clamp Techniques
KW  - Phenotype
KW  - Purines
KW  - pharmacology
KW  - Roscovitine
KW  - Single-Cell Analysis
KW  - Syndactyly
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nature09855
ER  -