Yeh, C-H

Propofol inhibits lipopolysaccharide-induced lung epithelial cell injury by reducing hypoxia-inducible factor-1alpha expression. [electronic resource] - British journal of anaesthesia Apr 2011 - 590-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1471-6771

10.1093/bja/aer005 doi


Acute Lung Injury--chemically induced
Anesthetics, Intravenous--pharmacology
Animals
Apoptosis--drug effects
Cells, Cultured
Cytokines--biosynthesis
Disease Models, Animal
Drug Evaluation, Preclinical--methods
Endotoxemia--chemically induced
Epithelial Cells--drug effects
Gene Expression Regulation--drug effects
Gene Knockdown Techniques
Humans
Hypoxia-Inducible Factor 1, alpha Subunit--biosynthesis
Lipopolysaccharides
Lung--metabolism
Mice
Mice, Inbred BALB C
Propofol--pharmacology
Reverse Transcriptase Polymerase Chain Reaction--methods