The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression. [electronic resource]
- Breast cancer research : BCR Feb 2011
- R19 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1465-542X
10.1186/bcr2828 doi
Adult Aged Aged, 80 and over Breast Neoplasms--genetics Cohort Studies DNA Methylation Female Gene Dosage Gene Expression Humans Kaplan-Meier Estimate Mammary Glands, Human--metabolism Middle Aged Neoplasm Staging Nuclear Proteins--genetics Phenotype Promoter Regions, Genetic Tumor Suppressor Protein p53--metabolism Ubiquitin-Protein Ligases--genetics Young Adult Seven in Absentia Proteins