Chan, Wing Man

Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1. [electronic resource] - Human molecular genetics May 2011 - 1738-50 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2083

10.1093/hmg/ddr049 doi


Active Transport, Cell Nucleus
Animals
Cell Line
Cell Nucleus--genetics
Disease Models, Animal
Drosophila--genetics
HEK293 Cells
Humans
Intracellular Space--genetics
Karyopherins--genetics
Neurodegenerative Diseases--genetics
Peptides--genetics
Protein Binding
Protein Structure, Tertiary
Protein Transport
Proteins--chemistry
Receptors, Cytoplasmic and Nuclear--genetics
Trinucleotide Repeat Expansion
Exportin 1 Protein