TY - GEN AU - Gildea,Derek E AU - Luetkemeier,Erin S AU - Bao,Xiaozhong AU - Loftus,Stacie K AU - Mackem,Susan AU - Yang,Yingzi AU - Pavan,William J AU - Biesecker,Leslie G TI - The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling SN - 1530-6860 PY - 2011///0628 KW - Animals KW - Blotting, Western KW - Eukaryotic Initiation Factor-3 KW - genetics KW - Genotype KW - Hedgehog Proteins KW - In Situ Hybridization KW - Kruppel-Like Transcription Factors KW - Mice KW - Mice, Inbred C3H KW - Mice, Inbred C57BL KW - Mutation KW - Nerve Tissue Proteins KW - Patched Receptors KW - Patched-1 Receptor KW - Phenotype KW - Polydactyly KW - Polymorphism, Genetic KW - Receptors, Cell Surface KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Zinc Finger Protein Gli3 N1 - Publication Type: Journal Article; Research Support, N.I.H., Intramural UR - https://doi.org/10.1096/fj.10-169771 ER -