TY - GEN AU - Gant,John C AU - Chen,Kuey-Chu AU - Norris,Christopher M AU - Kadish,Inga AU - Thibault,Olivier AU - Blalock,Eric M AU - Porter,Nada M AU - Landfield,Philip W TI - Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons SN - 1529-2401 PY - 2011///0401 KW - Aging KW - genetics KW - Animals KW - Calcium KW - metabolism KW - Calcium Channels, L-Type KW - Calcium Signaling KW - Cells, Cultured KW - Electrophysiology KW - Gene Knockdown Techniques KW - Genetic Vectors KW - Hippocampus KW - Homeostasis KW - drug effects KW - Immunohistochemistry KW - Male KW - Membrane Potentials KW - Microinjections KW - Patch-Clamp Techniques KW - Polymerase Chain Reaction KW - Pyramidal Cells KW - Rats KW - Rats, Inbred F344 KW - Ryanodine Receptor Calcium Release Channel KW - Sirolimus KW - pharmacology KW - Tacrolimus Binding Proteins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1523/JNEUROSCI.4805-10.2011 ER -