TY - GEN AU - Dowal,Louisa AU - Sim,Derek S AU - Dilks,James R AU - Blair,Price AU - Beaudry,Sarah AU - Denker,Bradley M AU - Koukos,Georgios AU - Kuliopulos,Athan AU - Flaumenhaft,Robert TI - Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1 SN - 1091-6490 PY - 2011///0414 KW - Allosteric Regulation KW - physiology KW - Animals KW - Antithrombins KW - metabolism KW - Calcium KW - Cell Line KW - Dogs KW - Epinephrine KW - Flow Cytometry KW - Luciferases KW - P-Selectin KW - Peptide Fragments KW - Platelet Aggregation KW - Protein Structure, Secondary KW - Receptor, PAR-1 KW - agonists KW - Receptors, G-Protein-Coupled KW - Signal Transduction KW - Thrombosis N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1014863108 ER -