Huang, Zhangjian <br/><br/>
Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies.  [electronic resource] 

 -  Journal of medicinal chemistry  Mar 2011 
 - 1356-64 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm101403g  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Inflammatory Agents, Non-Steroidal--adverse effects<br/>Carrageenan<br/>Cyclooxygenase Inhibitors--adverse effects<br/>Edema--chemically induced<br/>Esters<br/>Gastric Mucosa--drug effects<br/>Humans<br/>Hydroxamic Acids--adverse effects<br/>Ibuprofen--adverse effects<br/>Indomethacin--adverse effects<br/>Male<br/>Naproxen--adverse effects<br/>Nitric Oxide Donors--adverse effects<br/>Nitrogen Oxides--metabolism<br/>Prodrugs--adverse effects<br/>Rats<br/>Rats, Sprague-Dawley<br/>Stereoisomerism<br/>Stomach Ulcer--chemically induced<br/>Structure-Activity Relationship