TY  - GEN
AU  - Corvol,Jean-Christophe
AU  - Bonnet,Cécilia
AU  - Charbonnier-Beaupel,Fanny
AU  - Bonnet,Anne-Marie
AU  - Fiévet,Marie-Hélène
AU  - Bellanger,Agnès
AU  - Roze,Emmanuel
AU  - Meliksetyan,Gayané
AU  - Ben Djebara,Mouna
AU  - Hartmann,Andreas
AU  - Lacomblez,Lucette
AU  - Vrignaud,Cédric
AU  - Zahr,Noël
AU  - Agid,Yves
AU  - Costentin,Jean
AU  - Hulot,Jean-Sébastien
AU  - Vidailhet,Marie
TI  - The COMT Val158Met polymorphism affects the response to entacapone in Parkinson's disease: a randomized crossover clinical trial
SN  - 1531-8249
PY  - 2011///0316
KW  - Aged
KW  - Antiparkinson Agents
KW  - pharmacokinetics
KW  - Biological Availability
KW  - Catechol O-Methyltransferase
KW  - genetics
KW  - Catechol O-Methyltransferase Inhibitors
KW  - Catechols
KW  - Cross-Over Studies
KW  - Double-Blind Method
KW  - Enzyme Inhibitors
KW  - therapeutic use
KW  - Female
KW  - Genotype
KW  - Humans
KW  - Levodopa
KW  - metabolism
KW  - Male
KW  - Methionine
KW  - Middle Aged
KW  - Nitriles
KW  - Parkinson Disease
KW  - drug therapy
KW  - Pharmacogenetics
KW  - Polymorphism, Genetic
KW  - Valine
N1  - Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/ana.22155
ER  -