Corvol, Jean-Christophe <br/><br/>
The COMT Val158Met polymorphism affects the response to entacapone in Parkinson's disease: a randomized crossover clinical trial.  [electronic resource] 

 -  Annals of neurology  Jan 2011 
 - 111-8 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1531-8249 
<br/><br/><label>Standard No.: </label>10.1002/ana.22155  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aged<br/>Antiparkinson Agents--pharmacokinetics<br/>Biological Availability<br/>Catechol O-Methyltransferase--genetics<br/>Catechol O-Methyltransferase Inhibitors<br/>Catechols--pharmacokinetics<br/>Cross-Over Studies<br/>Double-Blind Method<br/>Enzyme Inhibitors--therapeutic use<br/>Female<br/>Genotype<br/>Humans<br/>Levodopa--metabolism<br/>Male<br/>Methionine--genetics<br/>Middle Aged<br/>Nitriles--pharmacokinetics<br/>Parkinson Disease--drug therapy<br/>Pharmacogenetics<br/>Polymorphism, Genetic<br/>Valine--genetics