TY - GEN AU - Nikam,Vandana S AU - Wecker,Gesa AU - Schermuly,Ralph AU - Rapp,Ulf AU - Szelepusa,Kirsten AU - Seeger,Werner AU - Voswinckel,Robert TI - Treprostinil inhibits the adhesion and differentiation of fibrocytes via the cyclic adenosine monophosphate-dependent and Ras-proximate protein-dependent inactivation of extracellular regulated kinase SN - 1535-4989 PY - 2011///1115 KW - Cell Adhesion KW - drug effects KW - Cell Differentiation KW - Cells, Cultured KW - Cyclic AMP KW - metabolism KW - Cyclic AMP Response Element-Binding Protein KW - Cyclic AMP-Dependent Protein Kinases KW - Epoprostenol KW - analogs & derivatives KW - Extracellular Matrix KW - Extracellular Signal-Regulated MAP Kinases KW - antagonists & inhibitors KW - Familial Primary Pulmonary Hypertension KW - Humans KW - Hypertension, Pulmonary KW - enzymology KW - Integrin alpha5 KW - Integrin beta1 KW - Leukocytes, Mononuclear KW - Mutation KW - Phosphorylation KW - Protein Kinase Inhibitors KW - pharmacology KW - Proto-Oncogene Proteins c-raf KW - Receptors, Prostaglandin KW - Signal Transduction KW - Time Factors KW - Transfection KW - rap1 GTP-Binding Proteins KW - genetics KW - ras Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1165/rcmb.2010-0240OC ER -