TY  - GEN
AU  - Paone,Daniel V
AU  - Nguyen,Diem N
AU  - Shaw,Anthony W
AU  - Burgey,Christopher S
AU  - Potteiger,Craig M
AU  - Deng,James Z
AU  - Mosser,Scott D
AU  - Salvatore,Christopher A
AU  - Yu,Sean
AU  - Roller,Shane
AU  - Kane,Stefanie A
AU  - Selnick,Harold G
AU  - Vacca,Joseph P
AU  - Williams,Theresa M
TI  - Orally bioavailable imidazoazepanes as calcitonin gene-related peptide (CGRP) receptor antagonists: discovery of MK-2918
SN  - 1464-3405
PY  - 2011///0815
KW  - Analgesics, Non-Narcotic
KW  - chemical synthesis
KW  - Animals
KW  - Azepines
KW  - Biological Availability
KW  - Calcitonin Gene-Related Peptide Receptor Antagonists
KW  - Caprolactam
KW  - chemistry
KW  - Cells, Cultured
KW  - Dogs
KW  - Humans
KW  - Imidazoles
KW  - Inhibitory Concentration 50
KW  - Macaca mulatta
KW  - Migraine Disorders
KW  - drug therapy
KW  - Molecular Structure
KW  - Rats
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2010.12.054
ER  -