Paone, Daniel V <br/><br/>
Orally bioavailable imidazoazepanes as calcitonin gene-related peptide (CGRP) receptor antagonists: discovery of MK-2918.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  May 2011 
 - 2683-6 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2010.12.054  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Analgesics, Non-Narcotic--chemical synthesis<br/>Animals<br/>Azepines--chemical synthesis<br/>Biological Availability<br/>Calcitonin Gene-Related Peptide Receptor Antagonists<br/>Caprolactam--chemistry<br/>Cells, Cultured<br/>Dogs<br/>Humans<br/>Imidazoles--chemical synthesis<br/>Inhibitory Concentration 50<br/>Macaca mulatta<br/>Migraine Disorders--drug therapy<br/>Molecular Structure<br/>Rats<br/>Structure-Activity Relationship