TY - GEN AU - Paolino,Magdalena AU - Thien,Christine B F AU - Gruber,Thomas AU - Hinterleitner,Reinhard AU - Baier,Gottfried AU - Langdon,Wallace Y AU - Penninger,Josef M TI - Essential role of E3 ubiquitin ligase activity in Cbl-b-regulated T cell functions SN - 1550-6606 PY - 2011///0428 KW - Adaptor Proteins, Signal Transducing KW - deficiency KW - Animals KW - Autoimmune Diseases KW - enzymology KW - Cell Line, Tumor KW - Clonal Anergy KW - genetics KW - Enzyme Activation KW - Female KW - Gene Knock-In Techniques KW - Immunophenotyping KW - Lymphocyte Activation KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Mice, Transgenic KW - Point Mutation KW - Proto-Oncogene Proteins c-cbl KW - RING Finger Domains KW - T-Lymphocyte Subsets KW - T-Lymphocytes, Cytotoxic KW - Ubiquitin-Protein Ligases KW - antagonists & inhibitors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.4049/jimmunol.1003390 ER -