TY  - GEN
AU  - Portoghese,P S
AU  - Larson,D L
AU  - Jiang,J B
AU  - Takemori,A E
AU  - Caruso,T P
TI  - 6beta-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxymorphinan(chlornaltrexamine) a potent opioid receptor alkylating agent with ultralong narcotic antagonist actitivty
SN  - 0022-2623
PY  - 1978///0925
KW  - Alkylating Agents
KW  - chemical synthesis
KW  - Analgesia
KW  - Binding, Competitive
KW  - Morphine
KW  - antagonists & inhibitors
KW  - Naloxone
KW  - analogs & derivatives
KW  - Naltrexone
KW  - Narcotic Antagonists
KW  - Nitrogen Mustard Compounds
KW  - Receptors, Opioid
KW  - drug effects
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1021/jm00205a002
ER  -