TY - GEN AU - Crowley,Steven D TI - Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. AT1 receptors in the kidney mediate the chronic hypertensive response to angiotensin II SN - 1522-1601 PY - 2011///0325 KW - Angiotensin II KW - metabolism KW - Angiotensin II Type 1 Receptor Blockers KW - therapeutic use KW - Animals KW - Antihypertensive Agents KW - Blood Pressure KW - drug effects KW - Humans KW - Hypertension KW - drug therapy KW - Kidney KW - Mice KW - Mice, Knockout KW - Receptor, Angiotensin, Type 1 KW - deficiency KW - Renin-Angiotensin System KW - Sympathetic Nervous System KW - Treatment Outcome N1 - Publication Type: Journal Article; Comment UR - https://doi.org/10.1152/japplphysiol.01160.2010 ER -