PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo. [electronic resource]
- Breast cancer research and treatment Nov 2011
- 85-96 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1573-7217
10.1007/s10549-010-1302-4 doi
Animals Antineoplastic Agents--chemistry Breast Neoplasms--drug therapy Cell Adhesion--drug effects Cell Cycle--drug effects Cell Line, Tumor Cell Movement--drug effects Cell Proliferation--drug effects Female Humans Mice Mice, Inbred BALB C Mice, Nude Neoplasm Metastasis Phosphorylation--drug effects Protein Binding Protein Kinase Inhibitors--chemistry Purines--chemistry Signal Transduction--drug effects Tumor Burden--drug effects Xenograft Model Antitumor Assays src-Family Kinases--antagonists & inhibitors