TY - GEN AU - Renouf,Daniel J AU - Moore,Malcolm J AU - Hedley,David AU - Gill,Sharlene AU - Jonker,Derek AU - Chen,Eric AU - Walde,David AU - Goel,Rakesh AU - Southwood,Bernadette AU - Gauthier,Isabelle AU - Walsh,Wendy AU - McIntosh,Lynn AU - Seymour,Lesley TI - A phase I/II study of the Src inhibitor saracatinib (AZD0530) in combination with gemcitabine in advanced pancreatic cancer SN - 1573-0646 PY - 2012///0611 KW - Administration, Oral KW - Aged KW - Antimetabolites, Antineoplastic KW - administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols KW - adverse effects KW - Benzodioxoles KW - Canada KW - Deoxycytidine KW - Disease Progression KW - Drug Administration Schedule KW - Female KW - Humans KW - Infusions, Intravenous KW - Kaplan-Meier Estimate KW - Male KW - Middle Aged KW - Pancreatic Neoplasms KW - drug therapy KW - Protein Kinase Inhibitors KW - Quinazolines KW - Treatment Outcome KW - Tumor Burden KW - drug effects KW - src-Family Kinases KW - antagonists & inhibitors KW - Gemcitabine N1 - Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s10637-010-9611-3 ER -