Yao, Song

Gene polymorphisms in cyclophosphamide metabolism pathway,treatment-related toxicity, and disease-free survival in SWOG 8897 clinical trial for breast cancer. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Dec 2010 - 6169-76 p. digital

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1557-3265

10.1158/1078-0432.CCR-10-0281 doi


Adult
Aged
Aged, 80 and over
Algorithms
Antineoplastic Agents, Alkylating--adverse effects
Antineoplastic Combined Chemotherapy Protocols--adverse effects
Aryl Hydrocarbon Hydroxylases--genetics
Breast Neoplasms--drug therapy
Carcinoma--drug therapy
Cyclophosphamide--adverse effects
Cytochrome P-450 CYP2B6
Cytochrome P-450 CYP3A--genetics
Disease-Free Survival
Female
Glutathione S-Transferase pi--genetics
Glutathione Transferase--genetics
Humans
Inactivation, Metabolic--genetics
Metabolic Networks and Pathways--genetics
Middle Aged
North America
Oxidoreductases, N-Demethylating--genetics
Polymorphism, Genetic--physiology