Schreck, Karisa C <br/><br/>
The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.  [electronic resource] 

 -  Clinical cancer research : an official journal of the American Association for Cancer Research  Dec 2010 
 - 6060-70 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1557-3265 
<br/><br/><label>Standard No.: </label>10.1158/1078-0432.CCR-10-1624  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Combined Chemotherapy Protocols--therapeutic use<br/>Basic Helix-Loop-Helix Transcription Factors--metabolism<br/>Brain Neoplasms--drug therapy<br/>Cell Line, Tumor<br/>Cyclic S-Oxides--administration & dosage<br/>Drug Evaluation, Preclinical<br/>Drug Resistance, Neoplasm--genetics<br/>Gene Expression Regulation, Neoplastic<br/>Glioblastoma--drug therapy<br/>Hedgehog Proteins--genetics<br/>Homeodomain Proteins--metabolism<br/>Humans<br/>Receptors, Notch--metabolism<br/>Signal Transduction--genetics<br/>Thiadiazoles--administration & dosage<br/>Transcription Factor HES-1<br/>Transcription Factors--genetics<br/>U937 Cells<br/>Veratrum Alkaloids--administration & dosage<br/>Zinc Finger Protein GLI1