Tissue Factor/ FVIIa prevents the extrinsic pathway of apoptosis by regulation of the tumor suppressor Death-Associated Protein Kinase 1 (DAPK1). [electronic resource]
- Thrombosis research Feb 2011
- 141-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1879-2472
10.1016/j.thromres.2010.11.015 doi
Apoptosis--drug effects Apoptosis Regulatory Proteins--biosynthesis Breast Neoplasms--genetics Calcium-Calmodulin-Dependent Protein Kinases--biosynthesis Caspase 8--metabolism Caspase Inhibitors Cell Line, Tumor Death-Associated Protein Kinases Enzyme Activation Factor VIIa--genetics Factor Xa--pharmacology Fas-Associated Death Domain Protein--metabolism Female Humans Male Phosphatidylinositol 3-Kinases--metabolism Phosphorylation Prostatic Neoplasms--genetics Proto-Oncogene Proteins c-akt--metabolism RNA, Messenger--genetics Receptor, PAR-1--biosynthesis Receptor, PAR-2--biosynthesis Recombinant Proteins--pharmacology Signal Transduction Thromboplastin--biosynthesis