TY - GEN AU - Pratap,Jitesh AU - Akech,Jacqueline AU - Wixted,John J AU - Szabo,Gabriela AU - Hussain,Sadiq AU - McGee-Lawrence,Meghan E AU - Li,Xiaodong AU - Bedard,Krystin AU - Dhillon,Robinder J AU - van Wijnen,Andre J AU - Stein,Janet L AU - Stein,Gary S AU - Westendorf,Jennifer J AU - Lian,Jane B TI - The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss SN - 1538-8514 PY - 2011///0328 KW - Animals KW - Bone Neoplasms KW - complications KW - Bone Resorption KW - Bone and Bones KW - diagnostic imaging KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Extremities KW - pathology KW - Histone Deacetylase Inhibitors KW - chemistry KW - Humans KW - Hydroxamic Acids KW - Mice KW - Mice, SCID KW - Osteolysis KW - Radiography KW - Tumor Burden KW - Tumor Microenvironment KW - Vorinostat KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1158/1535-7163.MCT-10-0572 ER -