TY  - GEN
AU  - Dhanya,Raveendra-Panickar
AU  - Sidique,Shyama
AU  - Sheffler,Douglas J
AU  - Nickols,Hilary Highfield
AU  - Herath,Ananda
AU  - Yang,Li
AU  - Dahl,Russell
AU  - Ardecky,Robert
AU  - Semenova,Svetlana
AU  - Markou,Athina
AU  - Conn,P Jeffrey
AU  - Cosford,Nicholas D P
TI  - Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self-administration in rats
SN  - 1520-4804
PY  - 2011///1109
KW  - Administration, Oral
KW  - Allosteric Regulation
KW  - Animals
KW  - Benzothiazoles
KW  - chemical synthesis
KW  - Biological Availability
KW  - Brain
KW  - metabolism
KW  - Chlorobenzoates
KW  - Cocaine
KW  - administration & dosage
KW  - Cocaine-Related Disorders
KW  - drug therapy
KW  - Drug Design
KW  - HEK293 Cells
KW  - Humans
KW  - Rats
KW  - Receptors, Metabotropic Glutamate
KW  - physiology
KW  - Self Administration
KW  - Structure-Activity Relationship
KW  - Tissue Distribution
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1021/jm1012165
ER  -