Dhanya, Raveendra-Panickar <br/><br/>
Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self-administration in rats.  [electronic resource] 

 -  Journal of medicinal chemistry  Jan 2011 
 - 342-53 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm1012165  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Allosteric Regulation<br/>Animals<br/>Benzothiazoles--chemical synthesis<br/>Biological Availability<br/>Brain--metabolism<br/>Chlorobenzoates--chemical synthesis<br/>Cocaine--administration & dosage<br/>Cocaine-Related Disorders--drug therapy<br/>Drug Design<br/>HEK293 Cells<br/>Humans<br/>Rats<br/>Receptors, Metabotropic Glutamate--physiology<br/>Self Administration<br/>Structure-Activity Relationship<br/>Tissue Distribution