Common allelic variants of the farnesyl diphosphate synthase gene influence the response of osteoporotic women to bisphosphonates. [electronic resource]
- The pharmacogenomics journal Jun 2012
- 227-32 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1473-1150
10.1038/tpj.2010.88 doi
Absorptiometry, Photon Adult Aged Aged, 80 and over Analysis of Variance Bone Density--drug effects Bone Density Conservation Agents--therapeutic use Bone Resorption--drug therapy Diphosphonates--therapeutic use Female Gene Frequency Geranyltranstransferase--genetics Haplotypes Humans Linear Models Linkage Disequilibrium Middle Aged Osteoporosis--diagnostic imaging Phenotype Polymorphism, Single Nucleotide Risk Assessment Risk Factors Spain Time Factors Treatment Outcome