TY - GEN AU - Dozmorov,Mikhail G AU - Azzarello,Joseph T AU - Wren,Jonathan D AU - Fung,Kar-Ming AU - Yang,Qing AU - Davis,Jeffrey S AU - Hurst,Robert E AU - Culkin,Daniel J AU - Penning,Trevor M AU - Lin,Hsueh-Kung TI - Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression SN - 1471-2407 PY - 2011///0331 KW - 3-Hydroxysteroid Dehydrogenases KW - genetics KW - Blotting, Western KW - Cell Line, Tumor KW - Cell Survival KW - Computational Biology KW - Dihydrotestosterone KW - metabolism KW - Disease Progression KW - Endothelial Cells KW - drug effects KW - Enzyme-Linked Immunosorbent Assay KW - Estradiol KW - Gene Expression Profiling KW - methods KW - Gene Expression Regulation, Neoplastic KW - Gene Regulatory Networks KW - Humans KW - Hydroxyprostaglandin Dehydrogenases KW - Insulin-Like Growth Factor I KW - Male KW - Neovascularization, Pathologic KW - enzymology KW - Oligonucleotide Array Sequence Analysis KW - Promoter Regions, Genetic KW - Prostatic Neoplasms KW - blood supply KW - Protein Kinase Inhibitors KW - pharmacology KW - Proto-Oncogene Proteins c-akt KW - antagonists & inhibitors KW - Receptor, IGF Type 1 KW - Receptors, Calcitriol KW - Retinoid X Receptors KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Transfection KW - Tumor Suppressor Protein p53 KW - Up-Regulation KW - Vascular Endothelial Growth Factor A N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1186/1471-2407-10-672 ER -